Kentaro Yamazaki Selected Research

Fluorouracil (Carac)

9/2020	Morphologic response to chemotherapy containing bevacizumab in patients with colorectal liver metastases: A post hoc analysis of the WJOG4407G phase III study.
1/2020	Phase Ib study of FOLFOXIRI plus ramucirumab as first-line treatment for patients with metastatic colorectal cancer.
11/2019	Exploration of potential prognostic biomarkers in aflibercept plus FOLFIRI in Japanese patients with metastatic colorectal cancer.
3/2019	Phase II trial of aflibercept with FOLFIRI as a second-line treatment for Japanese patients with metastatic colorectal cancer.
12/2018	Primary prophylactic granulocyte colony-stimulating factor according to ASCO guidelines has no preventive effect on febrile neutropenia in patients treated with docetaxel, cisplatin, and 5-fluorouracil chemotherapy.
5/2018	Risk factors for esophageal fistula in thoracic esophageal squamous cell carcinoma invading adjacent organs treated with definitive chemoradiotherapy: a monocentric case-control study.
1/2018	A Multicenter Clinical Phase II Study of FOLFOXIRI Plus Bevacizumab as First-line Therapy in Patients With Metastatic Colorectal Cancer: QUATTRO Study.
12/2016	Randomized study of FOLFIRI plus either panitumumab or bevacizumab for wild-type KRAS colorectal cancer-WJOG 6210G.
10/2015	Phase I study of TAS-102 and irinotecan combination therapy in Japanese patients with advanced colorectal cancer.
9/2015	Predictability of antitumor efficacy of cetuximab plus irinotecan based on skin rash severity according to observation period in patients with metastatic colorectal cancer following failure of fluorouracil, irinotecan and oxaliplatin.

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Kentaro Yamazaki Research Topics

Disease

83	Colorectal Neoplasms (Colorectal Cancer) 10/2022 - 07/2006
50	Neoplasms (Cancer) 10/2022 - 12/2005
17	Neutropenia 12/2021 - 07/2006
16	Stomach Neoplasms (Stomach Cancer) 06/2020 - 02/2007
10	Neoplasm Metastasis (Metastasis) 09/2020 - 12/2005
9	Disease Progression 10/2021 - 02/2007
8	Febrile Neutropenia 12/2021 - 04/2008
8	Colonic Neoplasms (Colon Cancer) 01/2021 - 04/2013
7	Diarrhea 07/2020 - 07/2006
7	Adenocarcinoma 06/2020 - 01/2009
6	Pancreatic Neoplasms (Pancreatic Cancer) 08/2022 - 01/2008
6	Hypertension (High Blood Pressure) 01/2018 - 12/2009
6	Nausea 01/2017 - 01/2008
5	Ascites 06/2020 - 10/2006
4	Hemorrhage 04/2021 - 12/2009
4	Esophageal Neoplasms (Esophageal Cancer) 10/2019 - 04/2008
4	Proteinuria 01/2018 - 11/2009
4	Fatigue 05/2015 - 04/2012
4	Anorexia 03/2015 - 01/2008
2	Lymphatic Metastasis 04/2022 - 12/2005
2	Peripheral Nervous System Diseases (PNS Diseases) 07/2021 - 04/2013
2	Thrombosis (Thrombus) 04/2021 - 12/2009
2	Rectal Neoplasms (Rectal Cancer) 01/2021 - 03/2015
2	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 12/2020 - 10/2011
2	Esophageal Squamous Cell Carcinoma 10/2018 - 05/2018
2	Esophageal Fistula 05/2018 - 08/2011
2	Leukopenia 01/2017 - 05/2015
2	Hand-Foot Syndrome 01/2017 - 11/2014
2	Carcinoma (Carcinomatosis) 10/2015 - 01/2002
2	Thrombocytopenia (Thrombopenia) 06/2015 - 11/2009
2	Hypoxia (Hypoxemia) 02/2013 - 01/2002
2	Squamous Cell Carcinoma of Head and Neck 01/2012 - 12/2011
2	Glioma (Gliomas) 04/2011 - 03/2011
1	Cancer Pain 01/2022
1	Mood Disorders (Mood Disorder) 01/2022
1	Biliary Tract Neoplasms (Biliary Tract Cancer) 10/2021
1	Gallbladder Neoplasms (Gallbladder Cancer) 10/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 04/2021
1	Venous Thrombosis (Deep-Vein Thrombosis) 04/2021

Drug/Important Bio-Agent (IBA)

37	Irinotecan (Camptosar)FDA LinkGeneric 12/2021 - 07/2006
31	Oxaliplatin (Eloxatin)FDA LinkGeneric 12/2021 - 09/2007
28	Fluorouracil (Carac)FDA LinkGeneric 09/2020 - 12/2005
23	Bevacizumab (Avastin)FDA Link 12/2021 - 08/2007
17	trifluridine tipiracil drug combinationIBA 07/2021 - 10/2012
13	Biomarkers (Surrogate Marker)IBA 04/2022 - 02/2011
12	Cisplatin (Platino)FDA LinkGeneric 10/2021 - 12/2005
12	Leucovorin (Folinic Acid)FDA Link 09/2020 - 07/2006
11	regorafenibIBA 04/2021 - 06/2015
10	Panitumumab (Vectibix)FDA Link 07/2021 - 05/2008
10	Cetuximab (Erbitux)FDA Link 06/2020 - 05/2008
8	RamucirumabIBA 11/2021 - 05/2015
8	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2021 - 01/2002
8	Monoclonal AntibodiesIBA 06/2021 - 08/2007
6	Circulating Tumor DNAIBA 04/2022 - 12/2016
5	Gemcitabine FDA Link 10/2021 - 12/2005
5	ErbB Receptors (EGF Receptor)IBA 07/2021 - 05/2008
4	Capecitabine (Xeloda)FDA Link 12/2021 - 11/2014
4	DNA (Deoxyribonucleic Acid)IBA 10/2020 - 09/2002
4	Paclitaxel (Taxol)FDA LinkGeneric 06/2020 - 12/2005
4	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2017 - 02/2013
4	S-1 plus cisplatinIBA 02/2013 - 12/2008
3	PlatinumIBA 10/2020 - 04/2008
3	afliberceptIBA 11/2019 - 08/2013
3	AntibodiesIBA 01/2019 - 12/2012
3	Docetaxel (Taxotere)FDA Link 12/2018 - 04/2008
3	Pharmaceutical PreparationsIBA 01/2017 - 01/2009
3	Codon (Codons)IBA 09/2013 - 03/2011
3	Epidermal Growth Factor (EGF)IBA 12/2012 - 04/2012
2	Immune Checkpoint InhibitorsIBA 01/2022 - 11/2016
2	Vascular Endothelial Growth Factor DIBA 10/2021 - 10/2020
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2021 - 12/2018
2	Proteins (Proteins, Gene)FDA Link 11/2019 - 12/2018
2	Serum AlbuminIBA 10/2019 - 12/2018
2	Alanine Transaminase (SGPT)IBA 01/2017 - 04/2013
2	BilirubinIBA 01/2017 - 04/2013
2	ParaffinIBA 01/2016 - 02/2011
2	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 08/2015 - 05/2015
2	PPAR gammaIBA 09/2014 - 06/2014
2	efatutazoneIBA 09/2014 - 06/2014
2	cediranib (AZD2171)IBA 08/2012 - 11/2009
2	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 04/2011 - 03/2011
1	Notch ReceptorsIBA 10/2022
1	N-acetyltalosaminuronic acid (NAT)IBA 08/2022
1	pembrolizumabIBA 01/2022
1	Volatile Oils (Essential Oils)IBA 01/2022
1	4-boronic acid benzophenoneIBA 10/2021

Therapy/Procedure

55	Drug Therapy (Chemotherapy) 10/2022 - 12/2005
46	Therapeutics 01/2022 - 07/2006
9	Chemoradiotherapy 10/2019 - 01/2008
4	Combination Drug Therapy (Combination Chemotherapy) 04/2012 - 06/2010
3	Radiotherapy 01/2018 - 12/2005
2	Neoadjuvant Therapy 08/2022 - 01/2022
2	Lymph Node Excision (Lymph Node Dissection) 04/2022 - 03/2015
2	Hepatectomy 01/2020 - 03/2018
2	Total Parenteral Nutrition 10/2019 - 02/2007
1	Pancreatectomy 08/2022
1	Aftercare (After-Treatment) 04/2022
1	Complementary Therapies (Alternative Medicine) 01/2022
1	Aromatherapy 01/2022
1	Time-to-Treatment 10/2021